Endowed with a gift of good academic career, C. S. Deshpande completed his Inter Science Examination in 1950 from Willingdon College, Sangli with a spectacular performance by standing FIRST in the University, winning all the University prizes and scholarships in all the subjects and creating records in Mathematics and in Aggregate total marks. (The 2nd rank student was behind him by as many as 70 marks i.e. by 10%).
After completing his B.E. (Electronics and Telecom.) from the College of Engineering, Pune, he joined the prestigious T.I.F.R. (Tata Institute of Fundamental Research) in 1954 as a research scholar in Nuclear Particle Accelerator Section. His name was specially recommended by his principal to Dr. Homi J Bhabha, the noted scientist and the founder of TIFR In the following year, he appeared at the I.E.S. ( Indian Engineering Services)